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Updated: Aug 23, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
[Treat calcified stenoses correctly]
Recha Blessing1, Tommaso Gori2,3
1Zentrum für Kardiologie, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.
Insights
Older patients with complex calcified coronary lesions require specialized interventional cardiology approaches. This review outlines treatment strategies and an algorithm to improve outcomes for these high-risk individuals.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Geriatric Cardiology
Abstract:
Due to the demographic changes with an increasing aging process of the population and the increasing incidence of comorbidities, such as diabetes mellitus, arterial hypertension, and chronic kidney disease, older patients with high-risk profiles and calcified coronary lesions are being treated more often in interventional cardiology. Despite advances in technical possibilities and materials, the treatment of severely calcified stenoses continues to be associated with an increased periprocedural risk of complications and poor long-term clinical outcomes. The purpose of this article is to discuss the various treatment approaches and summarize them in an algorithm for the treatment of severely calcified stenoses.
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