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Blue Light-Emitting Diode-Induced Direct C-H Functionalization of 1,4-Quinones with Aryl and Alkyl Boronic Acids

Souvik Guha1, Tejas Prabakar1, Subhabrata Sen1

  • 1Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Greater Noida, UP 201314, India.

The Journal of Organic Chemistry
|November 2, 2022
PubMed

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One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
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