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Recent Advances and Updates in Trigeminal Autonomic Cephalalgias.

Diana Y Wei1,2, Peter J Goadsby2,3,4

  • 1Department of Neurology, King's College Hospital, London, United Kingdom.

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|November 2, 2022
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Summary

Trigeminal autonomic cephalalgias (TACs) are severe unilateral headaches with autonomic symptoms. This review covers recent advances in understanding and treating these distinct headache disorders.

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Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Trigeminal autonomic cephalalgias (TACs) encompass distinct primary headache disorders.
  • TACs are characterized by unilateral head pain in the trigeminal nerve distribution and ipsilateral cranial autonomic symptoms.

Approach:

  • This review synthesizes recent research and clinical updates on TACs.
  • It outlines advances in the pathogenesis and treatment of each TAC subtype.

Key Points:

  • Includes hemicrania continua, cluster headache, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache (SUNH) variants.
  • Highlights progress in understanding the underlying mechanisms of TACs.
  • Discusses evolving therapeutic strategies for managing TACs.

Conclusions:

  • Significant progress has been made in the understanding and management of TACs.
  • This review provides a comprehensive update on the latest developments in the field.