Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Auditory Pathway01:15

Auditory Pathway

5.6K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.6K
The Cochlea01:13

The Cochlea

45.7K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.7K
Anatomy of the Ear01:16

Anatomy of the Ear

8.7K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
8.7K
Hearing01:31

Hearing

52.9K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
52.9K
Auditory Perception01:17

Auditory Perception

473
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...
473
Perceiving Loudness, Pitch, and Location01:21

Perceiving Loudness, Pitch, and Location

395
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
395

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy.

bioRxiv : the preprint server for biology·2026
Same author

Atypical Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease as Progressive Aphasia and Palinopsia: A Case Report.

Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology·2026
Same author

A Protocol for Microprism-Based Two-Photon Imaging Of The Lateral Cortex In The Mouse Inferior Colliculus.

Current protocols·2025
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Differential Myeloarchitecture of Subfields of the Mammalian Auditory Cortex: A Comparative Approach.

Brain, behavior and evolution·2025
Same author

Longitudinal awake imaging of mouse deep brain microvasculature with super-resolution ultrasound localization microscopy.

eLife·2025

Related Experiment Video

Updated: Aug 23, 2025

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve
11:27

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve

Published on: March 18, 2013

9.2K

Descending projections to the auditory midbrain: evolutionary considerations.

Silvio Macias1, Daniel A Llano2,3

  • 1Department of Biology, Texas A & M University, College Station, TX, USA.

Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
|November 3, 2022
PubMed
Summary

This study compares descending auditory pathways in mammals and frogs, exploring how these top-down modulators influence the inferior colliculus (IC) and torus semicircularis for auditory processing.

Keywords:
AnuranAuditory cortexBatCorticofugalEcholocationFrogInferior colliculusThalamus

More Related Videos

Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits
08:24

Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits

Published on: July 12, 2022

2.2K
In Vitro Wedge Slice Preparation for Mimicking In Vivo Neuronal Circuit Connectivity
10:31

In Vitro Wedge Slice Preparation for Mimicking In Vivo Neuronal Circuit Connectivity

Published on: August 18, 2020

5.6K

Related Experiment Videos

Last Updated: Aug 23, 2025

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve
11:27

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve

Published on: March 18, 2013

9.2K
Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits
08:24

Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits

Published on: July 12, 2022

2.2K
In Vitro Wedge Slice Preparation for Mimicking In Vivo Neuronal Circuit Connectivity
10:31

In Vitro Wedge Slice Preparation for Mimicking In Vivo Neuronal Circuit Connectivity

Published on: August 18, 2020

5.6K

Area of Science:

  • Neuroscience
  • Comparative Anatomy
  • Auditory System Research

Background:

  • Mammalian inferior colliculus (IC) receives extensive input from auditory cortex (AC) and other brain regions.
  • The frog torus semicircularis, an auditory integration center, has different descending inputs, lacking a direct cortical projection.

Purpose of the Study:

  • To comparatively analyze descending projections to auditory midbrain centers in mammals and amphibians.
  • To investigate the homology of thalamotectal projections and their interaction with cortical pathways.
  • To understand the functional significance of these descending pathways in auditory processing and behavior.

Main Methods:

  • Comparative analysis of neural pathways.
  • Review of existing literature on descending projections in mammals and amphibians.
  • Identification of key research questions for future experimental approaches.

Main Results:

  • Mammalian IC has diverse descending inputs, including from the AC, amygdala, and thalamus.
  • Frog torus semicircularis receives primary input from the posterior thalamus, lacking a dorsal pallium (cortical homolog) projection.
  • Descending projections are implicated in various behaviors, but their unified function remains unclear.

Conclusions:

  • Comparative analysis provides insights into the evolution and function of top-down auditory modulation.
  • The study highlights key questions regarding the homology of thalamotectal pathways and their interaction with cortical projections.
  • Future research should explore the behavioral significance of these pathways, particularly in species like anurans with complex acoustic navigation abilities.