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Published on: August 27, 2020
Characteristics of basilar artery atherosclerotic plaques in pontine infarctions: A high-resolution magnetic
Siqin Liu1, Yaowei Huang2, Yang Zou1
1Department of Neurology, Zhujiang Hospital, Southern Medical University, 253 Gongye Avenue Middle, Guangzhou City, Guangdong Province 510282, China.
Objective:
This study used a 3.0T high-resolution magnetic resonance imaging approach to explore basilar artery plaque characteristics in patients suffering from acute isolated pontine infarction.
Materials And Methods:
30 consecutive patients suffering from acute isolated pontine infarction were enrolled in this study and underwent examinations including high-resolution MRI assessment of the basilar artery within 7 days following infarction.
Results:
The basilar artery plaque burden of 16 patients with paramedian pontine infarction was 0.26±0.085, while the reconstruction index and enhancement rate index values in these patients were 1.097±0.133 and 1.750±0.447, respectively. In the 14 patients suffering from deep pontine infarction, these three values were 0.21±0.055, 0.896±0.223, and 1.285±0.611, respectively.These values differed significantly when comparing patients suffering from paramedian pontine infarction to those suffering from deep pontine infarction.
Conclusion:
This study suggests that the characteristics of basilar artery plaques differ between the two subtypes of pontine infarctions, which may account for the differences in prognosis associated with these two infarct subtypes.
Insights
Basilar artery plaque characteristics differ between paramedian and deep pontine infarctions. These findings in acute isolated pontine infarction may explain prognosis variations between subtypes.
Area of Science:
- Neurology
- Radiology
- Cardiovascular Imaging
Background:
- Acute isolated pontine infarction is a specific type of stroke.
- Understanding the underlying causes, such as basilar artery plaque characteristics, is crucial for prognosis.
Purpose of the Study:
- To investigate and compare the characteristics of basilar artery plaques in patients with acute isolated pontine infarction.
- To explore potential differences between subtypes of pontine infarction based on plaque morphology.
Main Methods:
- Utilized 3.0T high-resolution magnetic resonance imaging (MRI).
- Assessed basilar artery plaque burden, reconstruction index, and enhancement rate index.
- Enrolled 30 consecutive patients within 7 days of infarction.
Main Results:
- Significant differences in basilar artery plaque burden, reconstruction index, and enhancement rate index were observed between patients with paramedian and deep pontine infarction.
- Paramedian pontine infarction group showed plaque burden of 0.26±0.085, reconstruction index of 1.097±0.133, and enhancement rate index of 1.750±0.447.
- Deep pontine infarction group showed plaque burden of 0.21±0.055, reconstruction index of 0.896±0.223, and enhancement rate index of 1.285±0.611.
Conclusions:
- Basilar artery plaque characteristics vary between paramedian and deep pontine infarction subtypes.
- These plaque differences may contribute to the distinct prognoses observed in these two types of pontine infarction.
