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Updated: Aug 23, 2025
Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
Oral Teratoma with Hairy Polyp-Like Features: A Brief Report of a Rare Presentation
João Figueira Scarini1,2, Reydson Alcides de Lima-Souza1,2, Luccas Lavareze1,2
1Department of Pathology, Faculdade de Ciências Médicas, Universidade de Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Insights
A rare teratoma with hairy polyp features was found in a neonate's nasal cavity, causing feeding and breathing issues. Surgical removal is key for these congenital tumors.
Area of Science:
- Pediatric Oncology
- Developmental Biology
- Head and Neck Pathology
Background:
- Congenital tumors of the head and neck are rare but can cause significant morbidity.
- Teratomas, germ cell tumors with derivatives from all three embryonic germ layers, can occur in various locations.
Observation:
- A 21-day-old infant presented with a large tumor obstructing the nasopharynx and ethmoid plate via a cleft palate.
- The tumor caused severe feeding and respiratory distress.
Findings:
- Histopathology revealed a teratoma with mature adipose tissue, hair follicles, sebaceous glands, and neurovascular structures.
- Immature cartilaginous, glandular, bony, and myxoid tissues were present, alongside a biphenotypic pattern resembling a hairy polyp anteriorly.
Implications:
- This case highlights a complex teratoma with biphenotypic features, presenting diagnostic challenges.
- Early diagnosis and surgical intervention are crucial for managing such congenital tumors in neonates.
Abstract:
We present a 21-day-old female child presenting with a large oral epithelialized tumor implanted at the rhinopharynx and ethmoid plate through a cleft palate, associated with feeding and respiratory difficulties. The histopathological exam showed mature central adipose tissue, hair follicles, sebaceous glands, and neurovascular structures, lined by keratinized stratified squamous epithelium. Proliferative cartilaginous, glandular, lymphatic, bony, and immature myxoid tissue was seen at the posterior region and insertion. Despite the characterization of the tumor as a teratoma containing structures derived from the three embryonic leaflets, the anterior portion presented a microscopic bigeminal pattern fully compatible with hairy polyp.
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