Related Experiment Video
Updated: Aug 23, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
A perspective on diet, epigenetics and complex diseases: where is the field headed next?
Fabio Coppedè1, Marica Franzago2,3, Emiliano Giardina4,5
1Department of Translational Research & of New Surgical & Medical Technologies, University of Pisa, Pisa, 56126, Italy.
Abstract:
Dietary factors can regulate epigenetic processes during life, modulating the intracellular pools of metabolites necessary for epigenetic reactions and regulating the activity of epigenetic enzymes. Their effects are strong during the prenatal life, when epigenetic patterns are written, allowing organogenesis. However, interactions between diet and the epigenome continue throughout life and likely contribute to the onset and progression of various complex diseases. Here, we review the contribution of dietary factors to the epigenetic changes observed in complex diseases and suggest future steps to better address this issue, focusing on neurobehavioral, neuropsychiatric and neurodegenerative disorders, cardiovascular diseases, obesity and Type 2 diabetes, cancer and inflammatory skin diseases.
Related Concept Videos
Epigenetic Regulation
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Genomics
Introduction to Epidemiology
Microorganisms in Medicine and Therapeutics
Taste Buds and Receptors

