[Effect of a proliferation- stimulating preparation from bovine brain on cultured calf aortic endothelial cells]

A preparation from bovine brain (HS-3) stimulates the proliferation of a calf aortic cell line (BKEz-7) in concentrations between 50-200 micrograms/ml. It is especially effective at low inoculum cell density, it economizes fetal serum and is very efficient as additive for the improvement of inadequate sera. Important questions for the practical use as the properties of the preparation with regard to durability and sterile filtration have been investigated.