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Updated: Aug 23, 2025

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Optimal, Early Postoperative Management of Cardiac Transplant and Durable Left Ventricular Assist Recipients
Miriam Freundt1, Elizabeth Lavanga2, Christoph Brehm3
1Heart and Vascular Institute Critical Care Unit and Adult ECMO and Mechanical Circulatory Support Program, Penn State University College of Medicine, Hershey, PA, 17033, USA. mfreundt@pennstatehealth.psu.edu.
Purpose Of Review:
Summarize developments in the early postoperative care of patients undergoing cardiac transplantation or left ventricular assist device implantation. Provide a practical approach with personal insights to highly complex patients at risk for prolonged hospitalization.
Recent Findings:
Advancements in technology allow for percutaneous mechanical circulatory support of both the right and left ventricles either isolated or combined via subclavian and neck vessels. Since the adult heart allocation system has been changed to reduce waitlist mortality, the use of temporary mechanical circulatory support has increased. This has influenced preoperative optimization by enabling ambulation and majorly changed postoperative strategy. New doors have been opened for a multidisciplinary approach to facilitate rapid weaning of inotropic medications, limitation of sedation, early liberation from mechanical ventilation, and mobilization. Individualized percutaneous mechanical circulatory support offers new possibilities for the early postoperative management of highly complex patients undergoing cardiac transplantation or durable left ventricular assist device implantation.
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