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Updated: Aug 23, 2025

Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
Published on: March 1, 2017
Abstract:
In this special issue of Neuron, we present a series of opinions and reviews on neuro-immune interactions. Recent insights into how profoundly the nervous and immune systems affect each other, bolstered by trans-disciplinary collaboration, have revolutionized both neuroscience and immunology. Like a forest ecosystem, an organism thrives or withers depending on the balance of its components. Highlighted in this special issue is a small sampling of the ever-growing list of diseases influenced by dysfunctional neuro-immune crosstalk, ranging from multiple sclerosis and brain cancer to long COVID and Alzheimer's.
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