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Immunoception: Defining brain-regulated immunity.

Tamar Koren1, Asya Rolls1

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Researchers propose new terms for brain-immune interactions. "Immunoception" describes the brain

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Area of Science:

  • Neuroscience
  • Immunology
  • Physiology

Background:

  • Understanding homeostatic neuroimmune interactions is advancing.
  • Relevant terminology is needed to describe these complex relationships.

Purpose of the Study:

  • To define key terms for neuroimmune interactions.
  • To introduce the concepts of "immunoception" and the "immunengram".

Main Methods:

  • Conceptual analysis and definition of terms.
  • Literature review on neuroimmune pathways.

Main Results:

  • "Immunoception" is defined as the brain's bidirectional monitoring and control of immunity.
  • The "immunengram" is proposed as the distributed physiological trace storing immune information in the brain and peripheral memory cells.

Conclusions:

  • New terminology is essential for advancing the study of neuroimmune interactions.
  • The proposed terms provide a framework for understanding how the brain interacts with the immune system.