Cardiac anomaly detection considering an additive noise and convolutional distortion model of heart sound recordings

Cardiac auscultation is an essential point-of-care method used for the early diagnosis of heart diseases. Automatic analysis of heart sounds for abnormality detection is faced with the challenges of additive noise and sensor-dependent degradation. This paper aims to develop methods to address the cardiac abnormality detection problem when both of these components are present in the cardiac auscultation sound. We first mathematically analyze the effect of additive noise and convolutional distortion on short-term mel-filterbank energy-based features and a Convolutional Neural Network (CNN) layer. Based on the analysis, we propose a combination of linear and logarithmic spectrogram-image features. These 2D features are provided as input to a residual CNN network (ResNet) for heart sound abnormality detection. Experimental validation is performed first on an open-access, multiclass heart sound dataset where we analyzed the effect of additive noise by mixing lung sound noise with the recordings. In noisy conditions, the proposed method outperforms one of the best-performing methods in the literature achieving an Macc (mean of sensitivity and specificity) of 89.55% and an average F-1 score of 82.96%, respectively, when averaged over all noise levels. Next, we perform heart sound abnormality detection (binary classification) experiments on the 2016 Physionet/CinC Challenge dataset that involves noisy recordings obtained from multiple stethoscope sensors. The proposed method achieves significantly improved results compared to the conventional approaches on this dataset, in the presence of both additive noise and channel distortion, with an area under the ROC (receiver operating characteristics) curve (AUC) of 91.36%, F-1 score of 84.09%, and Macc of 85.08%. We also show that the proposed method shows the best mean accuracy across different source domains, including stethoscope and noise variability, demonstrating its effectiveness in different recording conditions. The proposed combination of linear and logarithmic features along with the ResNet classifier effectively minimizes the impact of background noise and sensor variability for classifying phonocardiogram (PCG) signals. The method thus paves the way toward developing computer-aided cardiac auscultation systems in noisy environments using low-cost stethoscopes.