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Characterizing Off-center MRI with ZTE.

Serhat Ilbey1, Matthias Jung2, Uzay Emir3

  • 1Dept. of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Zeitschrift Fur Medizinische Physik
|November 3, 2022
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Summary

Off-center excitation in zero echo time (ZTE) MRI corrects image distortions for extremities like the shoulder, knee, and hip. This technique allows high-bandwidth imaging without time or noise penalties, even when the anatomy isn't at the magnet's center.

Keywords:
Excitation profileOff-center MRIShort T2 imagingUnwanted slice selectionZTEZero echo time

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Physics
  • Biomedical Engineering

Background:

  • Zero echo time (ZTE) MRI sequences maximize acquisition bandwidth by activating readout gradients during RF pulses.
  • This simultaneous activation can cause unwanted slice selectivity and image distortions, particularly for off-center anatomy.
  • These artifacts are amplified when imaging extremities like the shoulder, knee, and hip, which are often not positioned at the magnet's isocenter.

Purpose of the Study:

  • To characterize and mitigate off-center image distortions in ZTE MRI of extremities.
  • To evaluate the effectiveness of adjusting RF pulse carrier frequency for off-center ZTE acquisitions.
  • To assess the impact of off-center excitation on image quality and acquisition parameters.

Main Methods:

  • Utilized radial encoding schemes in ZTE MRI, where slice profile distortions rotate with k-space trajectories.
  • Implemented RF pulse frequency shifting for each gradient setting to counteract modulations for off-center objects.
  • Compared off-center excitation ZTE MRI with standard isocenter excitation in phantom and in vivo studies of shoulder, knee, and hip at 1.5T and 3T.

Main Results:

  • Off-center excitation successfully mitigated distortion and blurriness artifacts in phantom and in vivo images of the shoulder, knee, and hip.
  • The improvements were achieved without any penalty in acquisition time or image noise.
  • No additional computational cost was required for the off-center excitation technique.

Conclusions:

  • Off-center excitation is a viable technique for ZTE MRI of extremities.
  • This method enables high-bandwidth imaging in clinical settings where precise isocenter positioning is impractical.
  • Facilitates improved image quality for shoulder, knee, and hip imaging using ZTE MRI.