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Role of non-coding RNA in immune microenvironment and anticancer therapy of gastric cancer

Liqiao Chen1, Jingyu Deng2

  • 1Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, People's Republic of China.

Journal of Molecular Medicine (Berlin, Germany)
|November 4, 2022
PubMed

Insights

Noncoding RNAs significantly impact gastric cancer

Area of Science:

  • Oncology
  • Molecular Biology
  • Immunology

Background:

  • Gastric cancer has high mortality rates globally.
  • Noncoding RNAs are crucial regulators in cancer.
  • Understanding their role in the gastric cancer immune microenvironment is vital.

Purpose of the Study:

  • To review the regulatory effects of noncoding RNAs on the gastric cancer immune microenvironment.
  • To explore the therapeutic prospects of noncoding RNAs in gastric cancer treatment.

Main Methods:

  • Literature review of noncoding RNAs in gastric cancer immunology.
  • Analysis of regulatory mechanisms and therapeutic potential.

Main Results:

  • Noncoding RNAs modulate tumor cells, immune cells, and the tumor microenvironment in gastric cancer.
  • These molecules offer potential for novel diagnostic markers and therapeutic strategies.

Conclusions:

  • Noncoding RNAs play complex roles in the gastric cancer immune landscape.
  • Targeting noncoding RNAs presents a promising avenue for improving gastric cancer patient prognosis and anticancer therapy.
Keywords:
Anticancer therapyBiomarkerGastric cancerImmune microenvironmentNon-coding RNA

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