Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

3.0K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.0K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

525
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
525
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

622
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
622

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.

Proceedings of the National Academy of Sciences of the United States of America·2012
Same author

Biosynthesis of ethyl oleate, a primer pheromone, in the honey bee (Apis mellifera L.).

Insect biochemistry and molecular biology·2012
Same author

Co-delivery strategies based on multifunctional nanocarriers for cancer therapy.

Current drug metabolism·2012
Same author

Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics·2012
Same author

Expression profile analysis of the polygalacturonase-inhibiting protein genes in rice and their responses to phytohormones and fungal infection.

Plant cell reports·2012
Same author

Characterizing natural dissolved organic matter in a freshly submerged catchment (Three Gorges Dam, China) using UV absorption, fluorescence spectroscopy and PARAFAC.

Water science and technology : a journal of the International Association on Water Pollution Research·2012

Related Experiment Video

Updated: Aug 23, 2025

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
06:19

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

285

Refraction development in anisometropic amblyopia with patching therapy.

Yao Chen1, Jingjing Zuo1, Yue Xiong1

  • 1School of Ophthalmology and Optometry, Affiliated Eye Hospital, State Key Laboratory of Ophthalmology, Optometry and Vision Science, Wenzhou Medical University, Wenzhou, China.

Frontiers in Medicine
|November 4, 2022
PubMed
Summary
This summary is machine-generated.

Patching therapy for anisometropic amblyopia led to significant refractive error changes in the amblyopic eye. Emmetropization continued post-therapy, but the fellow eye showed increased refractive changes.

Keywords:
amblyopiaanisometropiaanisometropic amblyopiaemmetropizationmyopic shiftpatching therapy

More Related Videos

The Measurement and Treatment of Suppression in Amblyopia
08:34

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

50.2K
Stereoacuity Improvement using Random-Dot Video Games
06:25

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

14.5K

Related Experiment Videos

Last Updated: Aug 23, 2025

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
06:19

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

285
The Measurement and Treatment of Suppression in Amblyopia
08:34

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

50.2K
Stereoacuity Improvement using Random-Dot Video Games
06:25

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

14.5K

Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Vision Science

Background:

  • Anisometropic amblyopia, a common cause of reduced vision in children, is often treated with patching therapy.
  • Understanding refractive development in treated amblyopic eyes is crucial for long-term visual outcomes.

Purpose of the Study:

  • To investigate the longitudinal changes in refractive error (spherical equivalent) in children with anisometropic amblyopia undergoing patching therapy.
  • To compare refractive development between the amblyopic eye and the fellow eye before, during, and after treatment.

Main Methods:

  • Retrospective review of 371 cases of unilateral anisometropic amblyopia treated with patching therapy (2003-2020).
  • Analysis of refractive error (SE) and best-corrected visual acuity (BCVA) over a mean follow-up of 4.76 years.
  • Linear mixed-effects models used to determine annual changes in SE for both eyes.

Main Results:

  • The amblyopic eye showed a greater annual change in SE (-0.32 D/yr) compared to the fellow eye (-0.16 D/yr).
  • During treatment, amblyopic eyes changed by -0.36 D/yr, and fellow eyes by -0.07 D/yr.
  • Post-treatment, amblyopic eyes continued to change by -0.27 D/yr, while fellow eyes showed an increased change of -0.18 D/yr.

Conclusions:

  • The amblyopic eye experiences significant and continuous refractive changes, even after patching therapy cessation.
  • While emmetropization persists in the treated amblyopic eye, the fellow eye exhibits accelerated refractive changes post-therapy.
  • These findings highlight the complex refractive adaptations in anisometropic amblyopia and the need for ongoing monitoring.