Related Experiment Video
Updated: Aug 23, 2025
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Cocooning strategy: Pertussis vaccination coverage rate of parents with a new-born in 2016 and 2017 in France
Clarisse Marchal1, Manon Belhassen1, Nicole Guiso2
1PELyon (Pharmaco Epidemiology Lyon), Lyon, France.
Insights
Pertussis vaccination coverage among new parents remains low, necessitating improved adult immunization. The cocooning strategy requires earlier vaccination timing for optimal infant protection against pertussis.
Area of Science:
- Public Health
- Immunization Strategies
- Epidemiology
Background:
- The cocooning strategy, initiated in 2004, aims to protect infants from pertussis by vaccinating their close contacts.
- This study evaluates the implementation of the cocooning strategy 12 years post-introduction.
Purpose of the Study:
- To assess pertussis vaccination coverage rates (VCR) among parents of newborns in France.
- To analyze the timing and context of pertussis vaccinations within the cocooning strategy.
Main Methods:
- Utilized French claims data (1/97th random sample) for women giving birth and men taking paternity leave in 2016-2017.
- Defined two periods: 'common practice' and 'parental project' for vaccination timing analysis.
Main Results:
- Pertussis VCR was approximately 47% for both mothers and fathers in 2016, slightly lower in 2017.
- About 25% of vaccinations occurred during the 'parental project' period.
- General practitioners were the primary prescribers, even for 'parental project' vaccinations.
Conclusions:
- Improving adult and senior pertussis immunization is crucial for infant protection.
- Cocooning vaccinations, especially those linked to parental projects, should be administered earlier, during pregnancy or immediately postpartum.
Background:
The "cocooning" strategy was introduced in 2004 to protect infants too young to be vaccinated against pertussis, by immunizing their parents and close relatives. The study objective was to assess its implementation 12 years after its introduction by estimating the pertussis vaccination coverage rates (VCR) among parents of newborns.
Materials And Methods:
Pertussis VCR were estimated among all women who gave birth and men who took paternity leave, in 2016 or 2017, from a 1/97th random sample of French claims data. Two distinct study periods were defined based on current recommendations for the cocooning strategy: the "common practice" and the "parental project" periods.
Results:
In 2016, the pertussis VCR of women having given birth and men having taken paternity leave was 47.2 and 47.1%, respectively (46.1 and 45.6% in 2017, respectively). About one quarter of vaccinations were performed during the "parental project" period, with the vaccine most frequently reimbursed during the month of childbirth for women (57.1% in 2016 and 49.4% in 2017) and before or during the month the paternity leave began for men (about 78% in both 2016 and 2017). General practitioners were the main prescribers in private practice, even during the "parental project" period.
Conclusion:
To optimize the protection for infants, the main objective of the cocooning strategy, pertussis immunization coverage of adults and seniors needs to be improved. Moreover, cocooning vaccination linked to a parental project needs to be performed earlier, during pregnancy (for those around the mother) or in immediate post-partum (e.g., during the maternity stay).
Related Concept Videos
01:51Vaccinations
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
01:28Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: