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Esben Uggerby Næser1,2, Klaus Søndergaard2

  • 1Diagnostisk Center, Regionshospitalet Silkeborg.

Ugeskrift for Laeger
|November 4, 2022
PubMed
Summary

Raynaud's phenomenon (RP) is a vasospastic disorder affecting extremities due to cold or stress. Early diagnosis of RP is crucial as it can signal underlying connective tissue diseases like systemic sclerosis.

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Area of Science:

  • Vascular Medicine
  • Rheumatology

Background:

  • Raynaud's phenomenon (RP) is a vasospastic condition affecting extremities, impacting 3-5% of the population.
  • RP can be primary or secondary to other medical conditions, notably connective tissue diseases.
  • RP may be an early indicator of systemic sclerosis, enabling timely intervention.

Approach:

  • This review synthesizes current knowledge on RP.
  • It covers causes, clinical manifestations, diagnostic strategies, and therapeutic options.
  • Focus is placed on the diagnostic utility of RP for systemic sclerosis.

Key Points:

  • RP involves episodic vasospasm in extremities triggered by cold or stress.
  • Secondary RP necessitates investigation for underlying systemic diseases.
  • Identifying RP early can lead to prompt diagnosis of conditions like systemic sclerosis.

Conclusions:

  • Raynaud's phenomenon serves as a potential early diagnostic marker for systemic sclerosis.
  • Understanding RP's diverse causes and presentations is vital for effective patient management.
  • This review provides a comprehensive overview for clinicians managing RP.

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