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Improving Biomedical ReQA With Consistent NLI-Transfer and Post-Whitening.

Jun Bai, Chuantao Yin, Zimeng Wu

    IEEE/ACM Transactions on Computational Biology and Bioinformatics
    |November 4, 2022
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    This study introduces a new framework for biomedical retrieval question answering (ReQA) to overcome data scarcity and overfitting. The approach enhances Dual-Encoder models for more robust and accurate biomedical information retrieval.

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    Area of Science:

    • Biomedical Informatics
    • Natural Language Processing
    • Machine Learning

    Background:

    • Retrieval Question Answering (ReQA) is crucial for information access.
    • Dual-Encoder models are effective for general ReQA but under-researched in biomedicine.
    • Biomedical ReQA faces challenges due to scarce annotated data, leading to overfitting.

    Purpose of the Study:

    • To develop a robust Dual-Encoder framework for biomedical ReQA.
    • To address the overfitting problem in training biomedical ReQA models.
    • To create new ReQA BioASQ datasets for advancing biomedical research.

    Main Methods:

    • Pre-training Dual-Encoder models on a modified Natural Language Inference (NLI) task to improve transferability.
    • Implementing consistent post-whitening to decorrelate sentence embeddings and reduce feature redundancy.
    • Training and evaluating the proposed framework on newly built ReQA BioASQ datasets.

    Main Results:

    • The proposed framework significantly improves the robustness and performance of biomedical ReQA.
    • Achieved promising results, outperforming various competitive methods in experiments.
    • Demonstrated enhanced transferability from NLI pre-training to biomedical ReQA tasks.

    Conclusions:

    • The developed framework effectively mitigates overfitting in biomedical ReQA.
    • The modified NLI pre-training and post-whitening techniques enhance Dual-Encoder model performance.
    • This work provides a valuable resource and methodology for biomedical information retrieval research.