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Candidal suppurative peripheral thrombophlebitis: recognition, prevention, and management.
Infection Control : IC
|January 1, 1986
Summary
Candida species can cause suppurative peripheral thrombophlebitis, a rare infection. Early diagnosis and combined surgical and antifungal treatment are crucial for managing this nosocomial fungal infection.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Hospital Epidemiology
Background:
- Suppurative peripheral thrombophlebitis is rarely attributed to Candida species.
- Nosocomial fungal infections pose significant challenges in acute-care settings.
Purpose of the Study:
- To investigate the occurrence and characteristics of candidal suppurative peripheral thrombophlebitis.
- To identify risk factors and evaluate treatment strategies for this rare fungal infection.
Main Methods:
- Retrospective analysis of seven patients diagnosed with candidal suppurative peripheral thrombophlebitis over 15 months.
- Clinical data collection including symptoms, laboratory results, preceding infections, antibiotic exposure, and treatment outcomes.
Main Results:
- Seven patients developed candidal suppurative peripheral thrombophlebitis, presenting with fever and tender palpable cords.
- Candida species were isolated from resected veins or pus; four patients had candidemia.
- Risk factors included prolonged broad-spectrum antibiotic use, preceding bacterial infections, and deficient catheter care.
Conclusions:
- Candida species should be considered in cases of suppurative peripheral thrombophlebitis, especially in hospitalized patients.
- Combined segmental venous resection and intravenous amphotericin B is a recommended therapeutic approach.
- Improved catheter care and judicious antibiotic use are essential for preventing such nosocomial infections.