Related Experiment Video
Updated: Aug 23, 2025
Pre-clinical Model of Cardiac Donation after Circulatory Death
Published on: August 2, 2019
Breaking barriers in cardiac donation after circulatory death
Mario Galván Ruiz1, María Del Val Groba Marco1, Michelle Tout Castellano2,3
1Department of Cardiology, University Hospital of Gran Canaria Doctor Negrín, Las Palmas, Spain.
Insights
Heart transplantation from controlled donation after circulatory death (cDCD) donors is a promising strategy. This case demonstrates successful heart transplants from cDCD donors, even with extended cold ischemia times, expanding the donor pool.
Area of Science:
- Cardiology
- Transplantation Surgery
- Organ Donation
Background:
- Controlled donation after circulatory death (cDCD) is an emerging strategy to expand the donor pool for heart transplantation (HT).
- Normothermic regional perfusion with extracorporeal membrane oxygenation is enabling HT from cDCD donors.
Background:
Heart transplant (HT) from controlled donation after circulatory death (cDCD) is an emerging strategy that is rapidly expanding and may help increase the heart donor pool.
Materials And Methods:
The use of thoracoabdominal normothermic regional perfusion with extracorporeal membrane oxygenation device has allowed to perform HT after cDCD in our country. We present a successful case of heart transplantation using a graft from cDCD with 201 min cold ischemia time.
Discussion And Conclusion:
HT from cDCD could be a good alternative to brain dead donation. This experience suggests than nonlocal cardiac from cDCD could tolerate long periods of cold ischemia time and break the main barriers with this technique.
More Related Videos
06:40A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
09:54Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022