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Updated: Aug 23, 2025

Murine Echocardiography and Ultrasound Imaging
Published on: August 8, 2010
Correlation between Murmurs and Echocardiographic Findings; From an Imaging Cardiologist Point of View
Sahrai Saeed1, Abukar Mohamed Ali1, Daanyaal Wasim1
1Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Insights
Heart murmurs in adults often lead to echocardiography, but auscultation findings poorly correlate with echocardiogram results, especially for diastolic murmurs. Careful physical examination is crucial for interpreting echocardiographic findings in heart valve disease.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Heart murmurs in adults are a frequent reason for echocardiography referrals in European cardiology clinics.
- Murmurs can signify minor age-related changes or significant valvular disease requiring intervention.
- Existing data suggest a generally poor correlation between auscultation findings and echocardiographic severity of heart valve disease.
Purpose of the Study:
- To review differential diagnoses of physiological and pathological heart murmurs.
- To describe current referral practices for echocardiography in patients with murmurs.
- To present a single-center analysis of the correlation between auscultation and echocardiography, focusing on aortic and mitral valve diseases.
Main Methods:
- Narrative review of existing literature.
- Analysis of a single-center experience correlating auscultation with echocardiographic findings.
- Focus on aortic and mitral valve diseases.
Main Results:
- Auscultation findings often show poor correlation with echocardiographic assessment of heart valve disease severity.
- Diastolic murmurs, in particular, may have a weak correlation with echocardiographic findings.
- Clinical examination, including careful auscultation, is essential for predicting and interpreting echocardiographic results.
Conclusions:
- A thorough cardiac auscultation before echocardiography is mandatory.
- Clinical examination and auscultation can aid in the interpretation of echocardiographic findings in adult patients with heart murmurs.
- Further research is needed to explore the correlation between clinical examination, point-of-care ultrasound, and standard echocardiography.
Abstract:
A heart murmur in adults is a common reason for referral for echocardiography at most general cardiology clinics in Europe. A murmur may indicate either a mild age-related valvular calcification or regurgitation, or represent a significant heart valve disease requiring valvular intervention. Generally, the correlation between murmurs by auscultation and severity of heart valve disease by echocardiography is poor. Particularly, the severity and characterization of diastolic murmurs by auscultation may poorly correlate with echocardiographic findings. This narrative review aims to summarize the differential diagnoses of physiological and pathological murmurs, describes the current referral practice of murmur patients for echocardiography, and presents a single-center experience on the correlation of auscultation and echocardiographic findings with a particular focus on aortic and mitral valve diseases. A careful auscultation of the heart prior to the echocardiogram is mandatory and may help to predict the echocardiographic findings and their interpretation in view of the clinical information. The correlation between clinical examination, point of care ultrasound and standard echocardiography is a matter of continued exploration.
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