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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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Predicting Infection Related Complications After Endovascular Repair of Infective Native Aortic Aneurysms
Warissara Jutidamrongphan1, Boonprasit Kritpracha2, Karl Sörelius3
1Department of Radiology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Summary
Endovascular aortic repair (EVAR) for infective native aortic aneurysm (INAA) can lead to infection-related complications (IRCs). Pre-operative clinical and CT scan features can predict these long-term IRC risks in INAA patients undergoing EVAR.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Radiology
Background:
- Endovascular aortic repair (EVAR) offers survival benefits for infective native aortic aneurysm (INAA) over open surgery.
- However, EVAR carries a risk of post-operative infection-related complications (IRCs).
Purpose of the Study:
- To identify clinical and computed tomography (CT) features associated with post-operative IRCs in INAA patients treated with EVAR.
- To develop a predictive model for long-term IRCs in patients with abdominal INAA undergoing EVAR.
Main Methods:
- Retrospective review of clinical data and CT scans for INAA patients treated with EVAR (2005-2020).
- Analysis of aneurysm features, peri-aortic involvement, and patient records for IRCs.
- Cox regression analysis to determine predictors and develop a 5-year IRC prediction model.
Main Results:
- 98 patients with abdominal INAA treated with EVAR were included; mean follow-up was 52 months.
- The 5-year IRC rate was 26%.
- Predictors of 5-year IRCs included female sex, renal insufficiency, positive blood culture, aneurysm diameter, and psoas muscle involvement. The predictive model achieved a C-index of 0.76.
Conclusions:
- Pre-operative clinical and CT findings can predict IRC risk after EVAR in INAA patients.
- Highlights the necessity for diligent clinical, laboratory, and radiological follow-up in these high-risk patients.
Keywords:
Computed tomographyEVARInfected aortic aneurysmInfection related complicationInfective native aortic aneurysmMycotic aortic aneurysmMore Related Videos
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