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Agomelatine Monotherapy for Autism-A Case Report.
Ahmed Naguy1, Saxby Pridmore2, Mohammed A Jamali3
1Naguy, MBBCh, MSc, Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Jamal Abdul-Nassir St, Shuwaikh, State of Kuwait.
Psychopharmacology Bulletin
|November 7, 2022
Summary
Agomelatine monotherapy shows promise for managing behavioral dyscontrol in individuals with autism spectrum disorder (ASD) and mild intellectual disability (ID) when other treatments fail. This approach offers a well-tolerated alternative to traditional antipsychotics, potentially opening new treatment avenues.
Area of Science:
- Neuroscience and Psychiatry
- Developmental Disorders
Background:
- Autism spectrum disorder (ASD) frequently presents with challenging behaviors requiring intervention.
- Pharmacotherapy is considered when psychosocial and educational strategies are insufficient.
- Current FDA-approved treatments like risperidone and aripiprazole carry significant metabolic and neuro-hormonal side effects.
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