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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Recent advances in paediatric sleep disordered breathing
Alison J B Garde1, Neil A Gibson2, Martin P Samuels3,4
1University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Insights
Childhood sleep disordered breathing (SDB) impacts neurodevelopment and growth. Simpler diagnostic tests and adenotonsillectomy are effective treatments, though alternative approaches exist for specific cases.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Neurodevelopmental Pediatrics
Background:
- Childhood sleep disordered breathing (SDB) is linked to adverse neurobehavioral, cardiovascular, and growth outcomes.
- Polysomnography is the gold standard for SDB diagnosis but is resource-intensive.
- Alternative diagnostic methods are being explored for efficiency and accessibility.
Purpose of the Study:
- To review current evidence on childhood sleep disordered breathing (SDB).
- To evaluate diagnostic tools beyond polysomnography.
- To discuss treatment strategies for SDB in children.
Main Methods:
- Review of recent scientific literature on childhood SDB.
- Analysis of diagnostic accuracy for polysomnography, cardiorespiratory polygraphy, and pulse oximetry.
- Evaluation of treatment outcomes for adenotonsillectomy, positive airway pressure, and other interventions.
Main Results:
- Cardiorespiratory polygraphy and pulse oximetry show promise for diagnosing obstructive sleep apnea (OSA) in children.
- Intracapsular tonsillectomy offers a safer alternative to traditional adenotonsillectomy.
- Weight loss and hypoglossal nerve stimulation may benefit specific pediatric SDB cases.
Conclusions:
- SDB significantly affects child development and health.
- Less invasive diagnostic methods are viable alternatives to polysomnography.
- Adenotonsillectomy remains a primary treatment, with tailored approaches for complex cases.
Abstract:
This article reviews the latest evidence pertaining to childhood sleep disordered breathing (SDB), which is associated with negative neurobehavioural, cardiovascular and growth outcomes. Polysomnography is the accepted gold standard for diagnosing SDB but is expensive and limited to specialist centres. Simpler tests such as cardiorespiratory polygraphy and pulse oximetry are probably sufficient for diagnosing obstructive sleep apnoea (OSA) in typically developing children, and new data-processing techniques may improve their accuracy. Adenotonsillectomy is the first-line treatment for OSA, with recent evidence showing that intracapsular tonsillectomy results in lower rates of adverse events than traditional techniques. Anti-inflammatory medication and positive airway pressure respiratory support are not always suitable or successful, although weight loss and hypoglossal nerve stimulation may help in select comorbid conditions.
Educational Aims:
To understand the clinical impact of childhood sleep disordered breathing (SDB).To understand that, while sleep laboratory polysomnography has been the gold standard for diagnosis of SDB, other diagnostic techniques exist with their own benefits and limitations.To recognise that adenotonsillectomy and positive pressure respiratory support are the mainstays of treating childhood SDB, but different approaches may be indicated in certain patient groups.
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