Related Experiment Video

Updated: Aug 22, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.0K

Asymmetric eye size in an infant

Brett D Edwards1, Joseph V Vayalumkal2, Rupesh Chawla3

  • 1Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal Officiel De L'Association Pour La Microbiologie Medicale Et L'Infectiologie Canada
|November 7, 2022
PubMed

Abstract:

Toxoplasmosis is an uncommon congenital infection in Canada, but one with potentially severe clinical manifestations, including fetal death. Neurologic and ocular manifestations are frequent in untreated disease; however, small eye size (microphthalmia) is a rare finding. This finding may be a marker of severe ocular disease. As universal screening does not occur in Canada, clinicians' early recognition is imperative, particularly given the lack of risk factors in many patients and the benefit that treatment may have even in initially asymptomatic disease. Here, we report a case of congenital toxoplasmosis and review the diagnostics and treatment of the infection.

Keywords:
Toxoplasma gondiicongenital toxoplasmosisocular toxoplasmosisopportunistic infectionsparasitic diseasespediatric infectionsprotozoal infectionspyrimethamine

More Related Videos

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
07:36

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children

Published on: September 1, 2018

23.8K
Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

10.7K

Related Experiment Videos

Last Updated: Aug 22, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.0K
Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
07:36

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children

Published on: September 1, 2018

23.8K
Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

10.7K

Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

1.7K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.7K
Muscles of the Eye01:20

Muscles of the Eye

1.7K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
1.7K

Articles linked to this work by shared authors, journal, and citation graph.

Reducing inappropriate infectious disease serology tests through the use of decision support in a provincial electronic health system.

Journal of clinical microbiology·2026

Rapid/point-of-care syphilis testing in high-income countries: insights and implementation challenges from the authors' experience in Canada.

Journal of clinical microbiology·2026

Extranodal Nasal Type NK/T-Cell Lymphoma of the Transverse Colon With Gastrointestinal Perforation in a 15-Year-Old: Durable Remission With Modified SMILE Chemotherapy and HSCT.

Case reports in hematology·2026

Assessing the Impact of an Sexually Transmitted Infections Nurse on the Delivery of Sexually Transmitted Infections/Human Immunodeficiency Virus Services in an Inner-City Emergency Department Using a Human Immunodeficiency Virus/Syphilis Point-of-Care Test During a Syphilis Outbreak in Alberta, Canada.

Sexually transmitted diseases·2026

Therapy With Doxycycline and Hydroxychloroquine Enables Surgical Excision of Ulcerated Cutaneous Granulomas in a Patient With Ataxia Telangiectasia.

Pediatric dermatology·2026

Wastewater-based surveillance of hepatitis A virus across municipalities and neighbourhoods in Alberta, Canada.

The Science of the total environment·2026

Infective endocarditis due to Lactococcus garvieae, an unusual emerging pathogen.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

Dual paradoxical reactions in tuberculous lymphadenitis during and after pregnancy: A case report.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

Influenza vaccination in solid organ transplant recipients: A systematic review and network meta-analysis of randomized trials.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

Impact of direct from clinical sample sequencing assays for infectious diseases diagnostics: A single-centre retrospective cohort study.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

An atypical travel-related infection from Jamaica to Canada.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

Successful use of bacteriophage therapy for a Staphylococcus aureus prosthetic joint infection in Canada.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026

Outcomes of patients with post-stroke epilepsy: A scoping review on quality of life, readmissions, costs, seizure recurrence, and medication adherence.

Epilepsia open·2026

Endogenous anti-Ebola virus GP1,2 antibodies interfere with detection of secreted glycoprotein in the blood of EVD patients.

Journal of virology·2026

Treatment of male osteoporosis: a narrative review and position statement by the ECTS Clinical Action Group.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Hepatocellular Carcinoma in the Eastern World: Screening, Diagnosis, Staging and Treatment.

Current pharmaceutical design·2026

HbA1C Variability as an Independent Predictor of Diabetic Retinopathy: A 10-Year Retrospective Nested Case-Control Study in a Middle Eastern Population.

Cureus·2026

Niosome-mediated melatonin delivery via SilMA/GelMA microneedles promotes healing of sleep deprivation-aggravated oral ulcers.

Regenerative biomaterials·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us