Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Behavioral assessment of visual toxicity.

H L Evans

    Environmental Health Perspectives
    |October 1, 1978
    PubMed
    Summary

    Animal behavioral methods assess drug-induced visual changes. Discrimination procedures are preferred over response rate measures for specific visual function testing in toxicology.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [(18)F]CF3-containing PET probes.

    Chemical communications (Cambridge, England)·2015
    Same author

    Reconstruction of the symphysis pubis to repair a complex midline hernia in the setting of congenital bladder exstrophy.

    Hernia : the journal of hernias and abdominal wall surgery·2014
    Same author

    Effect of corn dried distillers grains with solubles, conjugated linoleic acid, and ractopamine (paylean) on growth performance and fat characteristics of late finishing pigs.

    Journal of animal science·2012
    Same author

    The effect of corn distiller's dried grains with solubles, ractopamine, and conjugated linoleic acid on the carcass performance, meat quality, and shelf-life characteristics of fresh pork following three different storage methods.

    Meat science·2011
    Same author

    A Case of Traumatic Tetanus which Recovered under Antitoxin Injections.

    British medical journal·2010
    Same author

    Outbreak of carbapenem-resistant Acinetobacter baumannii among non-burn patients in a burn intensive care unit.

    The Journal of hospital infection·2010

    Area of Science:

    • Environmental toxicology
    • Animal behavior
    • Visual psychophysics

    Background:

    • Behavioral methods are crucial for evaluating visual system alterations caused by drugs and toxicants.
    • A diverse range of techniques exists, varying in complexity and specificity.

    Purpose of the Study:

    • To discuss the advantages of different behavioral methods for environmental toxicologists.
    • To highlight the importance of stimulus manipulation for identifying specific sensory functions.

    Main Methods:

    • Review of various animal behavioral methods for visual assessment.
    • Comparison of discrete-trial, multiple-choice discrimination procedures with response rate, speed, and reaction time measures.

    Main Results:

    • The percentage of correct choices in discrimination tasks is a more reliable indicator of specific visual functions than response rate measures.
    • Careful manipulation of stimulus values is essential for precise sensory function analysis.

    Conclusions:

    • Discrete-trial, multiple-choice discrimination procedures offer superior precision for assessing specific visual functions in toxicological studies.
    • Environmental toxicologists should carefully select behavioral methods based on the specific visual functions under investigation.

    Related Experiment Videos