Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

3.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.1K
Clinical Trials01:16

Clinical Trials

6.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
6.9K
Blinding01:11

Blinding

2.5K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.5K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

157
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
157
Blind Procedures02:07

Blind Procedures

10.8K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.8K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.1K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimates of vaccine effectiveness against measles and mumps: 14 years follow-up of a large cohort in Wales, UK.

International journal of epidemiology·2026
Same author

Perceptions of health misinformation on social media: patterns and predictors.

Frontiers in medicine·2026
Same author

Patient-specific and provider-specific predictors of urgent care referral to dermatology: A retrospective cohort and survey study.

JAAD international·2026
Same author

"More guidelines than rules": reconsidering key gaps in the 2025 American College of Rheumatology treatment recommendations for systemic lupus erythematosus: comment on the article by Sammaritano et al.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

An efficient approach to study ANA⁺ B cells in autoimmune diseases integrating flow cytometry with single-cell analysis.

Molecular medicine (Cambridge, Mass.)·2026
Same author

Bivalent RSV prefusion vaccine effectiveness against hospitalisation in older adults: meta-analysis of case-control studies in England, Wales, Scotland, and Northern Ireland.

The Lancet regional health. Europe·2026

Related Experiment Video

Updated: Aug 22, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

12.0K

A Provider-Based Approach to Address Racial Disparities in Lupus Clinical Trial Participation.

Nicole I Wanty1, Dexter L Cooper1, Andrew Simkus1

  • 1KDH Research and Communication, Atlanta, Georgia.

Arthritis Care & Research
|November 7, 2022
PubMed
Summary

An online educational course effectively trained medical providers to increase referrals of Black and Latino patients to lupus clinical trials (LCTs), improving knowledge and intentions. This addresses disparities in lupus research participation.

More Related Videos

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

3.8K
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.9K

Related Experiment Videos

Last Updated: Aug 22, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

12.0K
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

3.8K
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.9K

Area of Science:

  • Clinical trial recruitment
  • Health disparities research
  • Medical education technology

Background:

  • Clinical trial participation disparities disproportionately affect minority populations in diseases like lupus.
  • Improving minority representation in clinical trials is crucial for generalizable research findings.

Purpose of the Study:

  • To evaluate an online educational course designed to train healthcare providers to refer Black and Latino patients to lupus clinical trials (LCTs).

Main Methods:

  • The study employed a randomized, pretest/posttest design with medical and nursing providers.
  • Participants were assigned to an intervention group (online course) or a control group (no intervention).
  • Statistical analysis modeled the impact of the course on knowledge, attitudes, self-efficacy, and referral intentions.

Main Results:

  • The intervention group showed significantly higher posttest scores in knowledge, self-efficacy, and intentions to refer patients to LCTs compared to the control group.
  • Both medical and nursing providers in the intervention group demonstrated improved knowledge and referral intentions.
  • Course satisfaction was positively correlated with increased intentions to refer patients.

Conclusions:

  • The online educational course is an effective tool for educating medical providers about LCTs.
  • The course successfully enhanced providers' intentions to refer Black and Latino patients to lupus clinical trials, addressing participation gaps.