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Micronuclei frequency and renal function markers in gym members: The moderating role of supplement intake
Patrícia Molz1, Caroline Brand2, Diene da Silva Schlickmann3
1Graduate Program in Health Promotion, Department of Health Science, University of Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Rio Grande do Sul, Brazil; Laboratory of Experimental Nutrition, Department of Health Science, University of Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Rio Grande do Sul, Brazil; Graduate Program in Biosciences, Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
Abstract:
This research investigates the moderating role of dietary supplement intake in the relationship between MNi frequency and renal markers in gym members. A cross-sectional study was carried out with gym members of all sexes, between 20 and 59 years of age, with data on supplement use obtained via questionnaire. Renal markers (urea and creatinine) were assessed by blood collection. Buccal mucosa cells were collected to assess MNi frequency by buccal micronucleus cytome assay. Moderation was tested using multiple linear regression models by PROCESS macro for SPSS. Results showed significant interactions for supplement use (p = 0.001) and supplement type, ergogenic (p = 0.003) and sports food (p = 0.003), with MNi for urea. For creatinine, only supplement use showed interaction with MNi frequency (p = 0.048). In conclusion, supplement intake is a moderator in the relationship between MNi frequency and renal function markers in gym members.
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