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Aortic thrombosis as a dramatic vascular complication in COVID-19 disease
Charlotte Caudron1, Iannis Ben Abdallah1, Grégoire Détriché1
1Université Paris Cité, Paris, France; Assistance Publique-hôpitaux de Paris, hôpital Européen Georges Pompidou, Departments of Vascular Medicine and Vascular Surgery, Paris, France; Inserm UMR_S 1140, Innovations Thérapeutiques en Hémostase, Fondation Carpentier, laboratoire de recherches biochirurgicales, Paris, France.
Journal De Medecine Vasculaire
|November 7, 2022
Summary
Acute aortic thrombosis (AAT) is a rare but severe complication of COVID-19. This condition leads to high rates of mortality and limb amputation, highlighting the need for awareness and prompt management.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Cardiology
Background:
- COVID-19 has been associated with a hypercoagulable state.
- Acute aortic thrombosis (AAT) is a rare but serious vascular complication.
- Understanding the clinical outcomes of AAT in COVID-19 patients is crucial.
Purpose of the Study:
- To describe the clinical outcomes of patients with COVID-19 related acute aortic thrombosis (AAT).
Main Methods:
- Retrospective review of consecutive COVID-19 patients with AAT from April 2020 to August 2021.
- Prospective collection of clinical and radiological data.
- Analysis of patient demographics, clinical presentation, thrombus location, treatment strategies, and outcomes.
Main Results:
- Ten patients (90% male, mean age 64 years) were included.
- Common presentations included lower limb (90%) and mesenteric ischemia (20%).
- High 30-day mortality (30%) and major amputation rates (33%) were observed.
Conclusions:
- COVID-19 related AAT is a rare, devastating complication.
- AAT is associated with significant morbidity, including high mortality and amputation rates.
- Further research into prevention and management strategies is warranted.
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