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Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

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Recent advancements and perspective of ciprofloxacin-based antimicrobial polymers

Shreya Kanth1, Yashoda Malgar Puttaiahgowda1, Sonali Gupta1

  • 1Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.

Journal of Biomaterials Science. Polymer Edition
|November 8, 2022
PubMed

Insights

Polymers can carry the antibiotic ciprofloxacin, enhancing its antibacterial activity against resistant microbes. This review explores recent advances in polymer-ciprofloxacin conjugates for diverse applications.

Area of Science:

  • Microbiology
  • Polymer Science
  • Pharmacology

Background:

  • Rising global infections and antimicrobial resistance pose significant public health threats.
  • Ciprofloxacin, a fluoroquinolone antibiotic, faces increasing bacterial resistance.
  • Novel drug delivery systems are needed to overcome antimicrobial resistance.

Purpose of the Study:

  • To review recent advancements in using polymers as carriers for ciprofloxacin.
  • To explore the antibacterial efficacy of polymer-ciprofloxacin conjugates.
  • To discuss applications of these conjugates in various sectors.

Main Methods:

  • Literature review of publications from the last five years.
  • Analysis of studies on polymer-loaded or modified ciprofloxacin.
  • Examination of covalent bonding strategies between ciprofloxacin and polymers.

Main Results:

  • Polymers effectively serve as macromolecular carriers for ciprofloxacin.
  • Polymer conjugation can enhance the antibacterial spectrum and efficacy of ciprofloxacin.
  • Covalently bonded ciprofloxacin-polymer systems show promise.

Conclusions:

  • Polymer-ciprofloxacin conjugates represent a promising strategy to combat antimicrobial resistance.
  • These advanced materials have potential applications across multiple industries.
  • Further research into polymer-drug conjugates is warranted.
Keywords:
Ciprofloxacinantimicrobial activityapplicationpolymers

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