SPR Based Biosensing Chip for COVID-19 Diagnosis-A Review

Surface Plasmon Resonance (SPR) techniques are highly accurate in detecting biomolecular like blood group measurement, food adulteration, milk adulteration and recently developing as a rapid detection for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. In order to validate the clinical diagnosis, Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) of nasopharyngeal swabs has been utilized, which is time consuming and expensive. For fast and accurate detection of the SARS-CoV-2 virus, SPR based biosensing chips are described in this review article. SPR sensors have the potential to be employed for fast, accurate, and portable SARS-CoV-2 virus diagnosis. To combat the SARS-CoV-2 pandemic, there is considerable interest in creating innovative biosensors that are quick, reliable, and sensitive for COVID-19 diagnosis.