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Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

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Related Experiment Video

Updated: Jun 16, 2026

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy
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Quantitative Brain Morphometry of Portable Low-Field-Strength MRI Using Super-Resolution Machine Learning.

Juan Eugenio Iglesias1, Riana Schleicher1, Sonia Laguna1

  • 1From the Athinoula A. Martinos Center for Biomedical Imaging (J.E.I., M.S.R.), Department of Radiology (J.E.I., P.S., M.S.R.), Department of Neurology and Center for Genomic Medicine (R.S., W.T.K.), and Department of Emergency Medicine (B.M., J.N.G.), Massachusetts General Hospital and Harvard Medical School, 55 Fruit St, Boston, MA 02114; Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, UK (J.E.I., B.B.); Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Mass (J.E.I.); Swiss Federal Institute of Technology (ETH), Zurich, Switzerland (S.L.); Department of Neurology, Yale New Haven Hospital, New Haven, Conn (K.N.S.); and Department of Physics, Harvard University, Cambridge, Mass (M.S.R.).

Radiology
|November 8, 2022
PubMed
Summary

Portable MRI scans can be enhanced using a machine learning super-resolution algorithm. This method synthesizes higher resolution images from low-field scans, improving brain morphometry measurements for neuroimaging applications.

Failed At:

2026-06-19T13:48:57.052233+00:00

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