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Resistance to Poly (ADP-Ribose) Polymerase Inhibitors (PARPi): Mechanisms and Potential to Reverse

Christina R Washington1, Kathleen N Moore2

  • 1Stephenson Cancer Center, University of Oklahoma HSC, 800 NE 10th St, Suite 5050, Oklahoma City, OK, 73104, USA. Christina-washington@ouhsc.edu.

Current Oncology Reports
|November 8, 2022
PubMed
Abstract

Keywords:
BRCA mutationEpithelial ovarian cancerHomologous recombination deficiencyNiraparibOlaparibPARP inhibitor resistancePARP inhibitorsRestoration of homologous recombination proficiencyRucaparib

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