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Meningioma With Partial and Spontaneous Regression of Peritumoral Edema on Long-Term Follow Up
Bo-Seob Kim1, Tae-Young Jung1, Kyung-Sub Moon1
1Department of Neurosurgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.
Abstract:
Spontaneous regression of meningioma is rarely observed. We report a one person of an incidentally diagnosed meningioma with a spontaneous regression. The 73-year-old female patient without symptoms showed the right sphenoid meningioma with peritumoral edema. The meningioma was incidentally diagnosed and followed up by MRI for 10 years. The tumor shrank with a decrease of edema on T2 MRI. The initial volume of 58.59 cm3, regressed to 37.16 cm3.
Insights
Spontaneous regression of meningioma, a rare phenomenon, was observed in an incidentally diagnosed case. This right sphenoid meningioma significantly shrank over a decade of MRI monitoring.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- Meningiomas are typically slow-growing tumors of the meninges.
- Spontaneous regression of meningioma is exceptionally rare in clinical practice.
- Incidental findings often lead to long-term monitoring protocols.
Observation:
- A 73-year-old female presented with an incidentally discovered right sphenoid meningioma.
- The patient was asymptomatic and the tumor exhibited peritumoral edema.
- Magnetic Resonance Imaging (MRI) was used for follow-up over a 10-year period.
Findings:
- The meningioma demonstrated significant spontaneous regression in size.
- Initial tumor volume was 58.59 cm³; it decreased to 37.16 cm³.
- Associated peritumoral edema also showed a notable reduction on T2 MRI sequences.
Implications:
- This case highlights the possibility of unexpected tumor regression in meningioma.
- Further research may explore the mechanisms underlying spontaneous meningioma regression.
- Understanding such events could influence future surveillance and treatment strategies for meningioma.
