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A Case Series of Myocarditis Related to the COVID-19 Vaccine

Hayfa O Ahmed1, Mawada M Ahmed1, Omer Elrasheid1

  • 1Cardiology, Security Forces Hospital, Riyadh, SAU.

Cureus
|November 9, 2022
PubMed

Insights

Rare cases of perimyocarditis linked to the COVID-19 vaccine have been observed. Most patients with vaccine-related myocarditis/pericarditis recover fully, but some may experience persistent heart dysfunction.

Area of Science:

  • Cardiology
  • Vaccinology
  • Infectious Diseases

Background:

  • Messenger RNA (mRNA) COVID-19 vaccines have been associated with rare cases of perimyocarditis.
  • The incidence of these adverse events increased with the rise in vaccination rates.

Observation:

  • This case series details four distinct presentations of myocarditis/pericarditis following mRNA COVID-19 vaccination.
  • Patient outcomes varied, highlighting the spectrum of this rare vaccine side effect.

Findings:

  • Three out of four patients achieved full recovery within 1 to 12 weeks.
  • One patient exhibited persistent left ventricular systolic dysfunction, necessitating ongoing monitoring.

Implications:

  • While generally rare, vaccine-associated myocarditis/pericarditis requires careful monitoring and further investigation into long-term outcomes.
  • Understanding the varied presentations and recovery trajectories is crucial for clinical management and patient counseling.

Keywords:
covid-19myocarditispericarditisperimyocarditisvaccine

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