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Updated: Aug 22, 2025

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Published on: May 11, 2015
Ketosis-Prone Type 2 Diabetes Mellitus: An Unusual Presentation
Lana Makahleh1, Ahmad Othman1, Venkata Vedantam1
1Internal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.
Abstract:
Ketosis-prone type 2 diabetes is a form of diabetes that usually presents with diabetic ketoacidosis (DKA) in patients who are not insulin dependent. It is commonly seen in African, African American, and Hispanic populations. Although the pathogenesis is not fully understood yet, it is believed to be caused by stress-induced reversible beta-cell and alpha-cell dysfunction in the pancreas. Here, we describe the case of an 80-year-old white female with well-controlled type 2 diabetes mellitus who had unexplained DKA in the setting of a urinary tract infection. The patient's DKA resolved after administering appropriate therapy, and she did not require treatment with insulin on discharge.
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