Related Experiment Video

Updated: Aug 22, 2025

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

3.5K

Predicting early mortality following single-stage coronary artery or valve surgery and carotid endarterectomy

Marco Franchin1, Walter Dorigo2, Stefano Benussi3,4

  • 1Department of CardioThoracic and Vascular Surgery, ASST Settelaghi Universitary Teaching Hospital, Varese, Italy.

Journal of Cardiac Surgery
|November 9, 2022
PubMed

Insights

Single-stage surgery combining coronary/valve surgery and carotid endarterectomy is effective for high-risk patients. This approach demonstrated acceptably low 30-day mortality and stroke rates in a multicenter study.

Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Vascular Surgery

Background:

  • Management of patients with concurrent cardiac and extracranial carotid artery disease presents significant challenges.
  • Risk stratification is crucial for guiding surgical decisions in these complex cases.

Purpose of the Study:

  • To evaluate the outcomes of single-stage coronary/valve surgery (CVS) and carotid endarterectomy (CEA).
  • To identify predictors of 30-day mortality following combined procedures.

Main Methods:

  • A multicenter, retrospective analysis of prospectively maintained data from three academic hospitals.
  • Included patients underwent single-stage CVS (coronary artery bypass surgery or valve surgery) and CEA between 2000 and 2020.
  • Primary outcome was 30-day mortality; secondary outcomes included neurologic events and stroke/death composite endpoint.

Main Results:

  • 386 patients underwent combined procedures: CEA with CABG (63%), CEA with valve surgery (10.4%), and CEA with both (26.7%).
  • The 30-day mortality rate was 3.9%, with postoperative stroke occurring in 1.3% of patients.
  • Preoperative left heart insufficiency and postoperative stroke were significant predictors of 30-day mortality.

Conclusions:

  • A single-stage surgical approach for patients with coexisting cardiac and carotid disease is a viable and effective option.
  • The observed low rates of postoperative stroke and mortality support this strategy in carefully selected high-risk individuals.
Abstract

Keywords:
carotid endarterectomy and coronary artery bypass graft surgerycarotid endarterectomy and valve surgerypostoperative strokesingle stage intervention

More Related Videos

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.4K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.2K

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
22
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
16
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
22