Tracheal stent aspergillosis occurring after aortic allograft of the trachea

Alix Durliat1, Myriam Locatelli-Sanchez2, Florent Wallet1

  • 1Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service de Réanimation, Pierre-Bénite, France.

Abstract

Insights

A rare case of tracheal aspergilloma causing airway obstruction was successfully treated with antifungal therapy. This highlights a severe but treatable manifestation of fungal infection in intensive care settings.

Area of Science:

  • Pulmonology
  • Mycology
  • Critical Care Medicine

Background:

  • Aspergillosis presents with diverse clinical forms, including severe invasive manifestations and less common but critical conditions requiring intensive care.
  • Tracheal aspergilloma, a fungal ball in the trachea, is a rare complication that can lead to significant airway obstruction.

Approach:

  • This study reports a unique case of tracheal aspergilloma obstructing the airway in a patient within the intensive care unit (ICU).
  • The aspergilloma formed within a tracheal stent, a device previously implanted for tracheal cancer following an allograft procedure.
  • Treatment involved a combination of local and systemic antifungal medications.

Key Points:

  • Tracheal aspergilloma can cause life-threatening tracheal obstruction, particularly in patients with implants like tracheal stents.
  • Successful management was achieved using a combined local and systemic antifungal treatment strategy.
  • This case underscores the importance of considering fungal infections in complex airway obstruction scenarios.

Conclusions:

  • Tracheal aspergilloma is a rare but serious complication that can occur in patients with tracheal stents.
  • Prompt diagnosis and a combined therapeutic approach of local and systemic antifungals can lead to successful outcomes.
  • Further research into endobronchial Aspergillus infections is warranted to improve patient management.

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