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Updated: Aug 22, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Developing Ru-Catalysts for Asymmetric Transfer Hydrogenation of Acyclic Imines
Dongxu He1,2, Chen Xu2, Xiangyou Xing2
1School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Abstract:
Asymmetric transfer hydrogenation (ATH) of acyclic imines has been rarely reported by using Ru-based catalysts. In this manuscript, employing Ru-catalysts with minimal stereogenicity in combination with formic acid/triethylamine as the hydrogen donor enables a highly efficient ATH of N-diphenylphosphinyl acyclic imines. These substrates that include various aryl alkyl and heteroaryl alkyl substituted imines were all compatible with this catalytic system, and the corresponding reduced amines were obtained with excellent enantiomeric excess (ee's) and yields.
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