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    Area of Science:

    • Biomedical optics
    • Ultrasound technology
    • Medical imaging

    Background:

    • Photoacoustic imaging (PAI) uses sound waves for tissue analysis.
    • Current PAI systems with single transducer arrays have limited field of view and resolution.
    • Capacitive micromachined ultrasonic transducers (CMUTs) offer advantages in bandwidth and cost for PAI.

    Purpose of the Study:

    • To introduce a multiperspective PAI (MP-PAI) approach using multiple CMUTs on a flexible array.
    • To improve field of view, resolution, and contrast in PAI.
    • To evaluate the effectiveness of MP-PAI with coherent and incoherent compounding methods.

    Main Methods:

    • Developed a flexible array with multiple CMUTs for MP-PAI.
    • Conducted in vitro experiments using a plaque-mimicking phantom.
    • Performed numerical studies to assess MP-PAI performance with varying transducer numbers and angular coverage.

    Main Results:

    • MP-PAI with three CMUTs increased generalized-contrast-to-noise ratio (gCNR) by 20% and peak signal-to-noise ratio (PSNR) by 2 dB.
    • MP-PAI doubled structural coverage compared to single CMUT setups.
    • Numerical studies showed image quality improvements up to threefold with 15 transducers and increased angular coverage.

    Conclusions:

    • MP-PAI significantly improves overall image quality, resolution, and contrast.
    • The number of transducers and angular coverage directly correlate with image quality enhancement.
    • MP-PAI demonstrates superior ability in resolving structural information within phantoms.