[Malignant paraganglioma mimicking multiple myeloma]
Toshikage Nagao1, Kana Bando1, Ayuko Iura1
1Department of Hematology, Tokyo Medical and Dental University Hospital.
[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|November 9, 2022
Summary
Malignant paraganglioma can mimic multiple myeloma with bone lesions and hypercalcemia. This case highlights the importance of considering paraganglioma in patients with unexplained osteolytic lesions and elevated IgG.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Multiple myeloma is a plasma cell malignancy characterized by bone lesions, hypercalcemia, and elevated immunoglobulins.
- Malignant paraganglioma is a rare neuroendocrine tumor that can metastasize to bone, presenting with skeletal-related events.
- Clinical presentation of bone metastases from malignant paraganglioma can overlap with multiple myeloma, leading to diagnostic challenges.
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