Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

303
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
303
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

412
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
412
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

186
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
186
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

297
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
297
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

396
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
396
Glaucoma: Overview01:25

Glaucoma: Overview

695
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
695

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Large colloid drusen.

Eye (London, England)·2026
Same author

Outcomes of Post-Traumatic Pediatric Endophthalmitis Following 25-Gauge Pars Plana Vitrectomy.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2026
Same author

Assessing the Role of Statins as an Adjunctive Anti-VEGF Therapy for Clinically Significant Macular Edema (CSME) in Type 2 Diabetes Mellitus.

Romanian journal of ophthalmology·2026
Same author

Vitreous transcriptomic profiling reveals miR-4762 as a potential diagnostic biomarker and modulator of disease pathophysiology in Tubercular Uveitis.

Tuberculosis (Edinburgh, Scotland)·2026
Same author

Spontaneously Resolved Lipemia Retinalis.

Ophthalmology. Retina·2026
Same author

Periocular Leukoderma Associated With Atropine Eye Drops.

JAMA ophthalmology·2025
Same journal

Ocular toxoplasmosis in Latin American and European patients: clinical characteristics, visual outcomes, and recurrence patterns.

Journal of ophthalmic inflammation and infection·2026
Same journal

Severe corneal melting with necrotic sloughing in Acanthamoeba keratitis mimicking corneal endotheliitis.

Journal of ophthalmic inflammation and infection·2026
Same journal

Delayed-onset cytomegalovirus retinitis after 0.2 µg/day fluocinolone acetonide implantation: a case series.

Journal of ophthalmic inflammation and infection·2026
Same journal

Evaluation of corneal intrastromal voriconazole injection as an adjuvant approach in recalcitrant fungal keratitis.

Journal of ophthalmic inflammation and infection·2026
Same journal

Occlusive retinal vasculopathy on ultrawide-field fluorescein angiography in intraocular cytomegalovirus infection: a case series.

Journal of ophthalmic inflammation and infection·2026
Same journal

Nocardia brasiliensis endophthalmitis initially misdiagnosed as uveitis: a case report.

Journal of ophthalmic inflammation and infection·2026
See all related articles

Related Experiment Video

Updated: Aug 22, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

1.8K

Tubercular serpiginous choroiditis.

Reema Bansal1, Vishali Gupta2

  • 1Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India. drreemab@rediffmail.com.

Journal of Ophthalmic Inflammation and Infection
|November 9, 2022
PubMed
Summary
This summary is machine-generated.

Tuberculosis (TB) can cause serpiginous choroiditis, an inflammatory eye condition. Early diagnosis and treatment with anti-TB therapy and corticosteroids are crucial for managing this vision-threatening disease.

Keywords:
Immune mechanismsPathogenesisSerpiginous choroiditisSerpiginous-like choroiditisTubercular

More Related Videos

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.8K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K

Related Experiment Videos

Last Updated: Aug 22, 2025

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

1.8K
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.8K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Immunology

Background:

  • Serpiginous choroiditis, also known as serpiginous-like choroiditis or multifocal serpiginoid choroiditis (MSC), is associated with tuberculosis (TB) globally, particularly in endemic regions.
  • Mycobacterium tuberculosis (MTB) is implicated as a direct or indirect infectious trigger for this ocular inflammation, with emerging evidence supporting immune-mediated mechanisms.

Purpose of the Study:

  • To elucidate the association between tuberculosis and serpiginous choroiditis.
  • To describe the clinical presentation, diagnostic methods, and therapeutic strategies for tubercular serpiginous-like choroiditis.

Main Methods:

  • Review of clinicopathological reports and animal models.
  • Clinical diagnosis based on characteristic multifocal, serpiginoid lesions.
  • Corroborative diagnostic tests including tuberculin skin test, QuantiFERON-TB Gold, and chest imaging for systemic TB evidence.

Main Results:

  • Tubercular serpiginous-like choroiditis typically affects young to middle-aged males.
  • Lesions are multifocal, evolving from discrete to confluent in a serpiginoid pattern, affecting both peripheral and posterior retina.
  • Fundus imaging, particularly autofluorescence, aids in monitoring treatment response.

Conclusions:

  • Diagnosis of tubercular serpiginous-like choroiditis is primarily clinical, supported by specific diagnostic tests.
  • Management involves systemic corticosteroids to control inflammation and anti-TB therapy (ATT) to prevent recurrence.
  • Immunosuppressive agents may be necessary for severe or refractory cases.