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Post-Traumatic Stress Disorder after Stroke: A Systematic Review.
Wai Kwong Tang1, Lisha Wang1, Kelvin K F Tsoi2
1Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China.
Neurology India
|November 10, 2022
Summary
Post-traumatic stress disorder (PTSD) affects 16.5% of stroke survivors, leading to chronic symptoms and reduced quality of life. Early identification and treatment of PTSD in stroke patients are crucial.
Area of Science:
- Neurology
- Psychiatry
- Clinical Psychology
Background:
- Post-traumatic stress disorder (PTSD) is a significant comorbidity following stroke.
- Understanding the prevalence and impact of PTSD after stroke is critical for patient outcomes.
Approach:
- Systematic review of published studies on PTSD in stroke patients.
- Inclusion criteria: >10 adult patients, diagnosed with PTSD post-stroke.
- Databases searched: PubMed, EMBASE, PsycINFO, Ovid Nursing.
Key Points:
- PTSD frequency after stroke ranges from 3% to 31% (weighted mean 16.5%).
- Associated factors include premorbid neuroticism, negative affect, maladaptive coping, comorbid depression/anxiety, and psychological distress.
- Positive factors: good social support reduces PTSD risk.
- Negative impacts: reduced quality of life, physical functioning, and medication compliance.
Conclusions:
- PTSD is a common and chronic condition post-stroke.
- Further research needed on time course, neurochemical factors, and brain circuits.
- Randomized controlled trials for PTSD treatment in stroke survivors are warranted.

