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Spectrum of Neurological Manifestations of COVID-19 Data from a Tertiary Care Hospital

Akshay Louis Dias1, B S Raghavendra2, Safwan Ahmed2

  • 1Department of General Medicine, Fr Muller Medical College, Mangalore, Karnataka, India.

Neurology India
|November 10, 2022
PubMed

Insights

Neurological complications affect nearly 2% of coronavirus disease 2019 (COVID-19) patients, including stroke and encephalopathy. Early recognition of these extrapulmonary symptoms is vital for improving patient outcomes and reducing mortality.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) primarily affects the respiratory system but also impacts other organs.
  • Extrapulmonary manifestations of COVID-19 require further investigation beyond pulmonary involvement.
  • Understanding neurological involvement is crucial for comprehensive patient care.

Purpose of the Study:

  • To detail the neurological effects of COVID-19 on the central and peripheral nervous systems.
  • To identify risk factors associated with neurological complications in COVID-19 patients.
  • To evaluate the outcomes for COVID-19 patients experiencing neurological symptoms.

Main Methods:

  • Assessment of all patients testing positive for SARS-CoV-2 RNA via PCR.
  • Collection of detailed clinical histories and laboratory findings.
  • Statistical analysis using percentages, means, and frequencies.

Main Results:

  • Neurological manifestations were observed in 1.96% (17 out of 864) of COVID-19 patients.
  • Common neurological presentations included acute cerebrovascular accidents (stroke), paraplegia, and encephalopathy.
  • Among patients with stroke, 50% (5 out of 10) died, highlighting the severity of these complications.

Conclusions:

  • Neurological manifestations are a significant, though less common, feature of COVID-19.
  • Awareness of the diverse neurological signs and symptoms is essential for prompt diagnosis.
  • Early detection and treatment of neurological complications can mitigate mortality and morbidity in COVID-19 patients.
Abstract

Keywords:
COVID-19neurological manifestationsstroke

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