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Updated: Aug 22, 2025
Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
Published on: August 2, 2021
Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic
Wei Zheng1, Xin-Yang Zhang1, Rui Xu1
1The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Objective:
We performed this systemic review to investigate the therapeutic potential and safety of adjunctive accelerated repetitive transcranial magnetic stimulation (aTMS) for older patients with depression.
Methods:
We included published randomized clinical trials (RCTs) and observational studies targeting adjunctive aTMS for older patients with depression.
Results:
Two open-label self-controlled studies (n = 29) fulfilled the criteria for inclusion. The included studies reported significant improvements in depressive symptoms from baseline to post-aTMS (all Ps < 0.05). One study reported a dropout rate of 10.5% (2/19). Mild headache was the most common adverse reaction.
Conclusion:
The currently available evidence from two open-label self-controlled studies indicates that adjunctive aTMS is a safe and effective therapy for older patients with depression.
