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Related Concept Videos

Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

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The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
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Extraction: Advanced Methods00:56

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Related Experiment Video

Updated: Aug 22, 2025

Uniportal Full Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
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Posterior component separation with TAR: lessons learned from our first consecutive 52 cases.

Gianpaolo Marte1, A Tufo2, A Ferronetti3

  • 1Department of General Surgery, Ospedale del Mare Hospital, Via Enrico Russo, 11, 80147, Naples, Italy. gianpaolo.marte@gmail.com.

Updates in Surgery
|November 10, 2022
PubMed
Summary
This summary is machine-generated.

Posterior component separation with transversus abdominis release (PCS-TAR) effectively repairs complex incisional hernias with low recurrence rates. This technique is a valuable option for complex ventral hernias, even in patients with comorbidities.

Keywords:
Complex ventral herniaComponent separationIncisional hernia repairPosterior component separationTARTransversus abdominis release

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Area of Science:

  • Abdominal Wall Reconstruction
  • Hernia Surgery
  • Surgical Techniques

Background:

  • Complex incisional hernias (IH) pose significant surgical challenges.
  • The posterior component separation with transversus abdominis release (PCS-TAR) is increasingly used for complex abdominal wall defects.
  • PCS-TAR has shown promise in managing recurrent IH.

Purpose of the Study:

  • To evaluate the reproducibility of the PCS-TAR procedure.
  • To describe the surgical technique, postoperative complications, and recurrence rates in a cohort of complex IH patients.
  • To assess the efficacy of PCS-TAR in a real-world clinical setting.

Main Methods:

  • Retrospective review of 52 consecutive patients with complex IH undergoing PCS-TAR between May 2014 and November 2019.
  • Data collected included patient demographics, defect characteristics, operative details, and postoperative outcomes.
  • Analysis of complications (Clavien-Dindo classification), surgical site infections (SSI), and recurrence rates.

Main Results:

  • Posterior fascial closure achieved in all patients; anterior fascial closure in 56%.
  • Low rates of complications (27% minor, 1.9% major) and SSI (3.8%).
  • Recurrence rate was 1.9% at a mean follow-up of 28 months. Larger defect area (>600 cm²) was associated with major complications.

Conclusions:

  • PCS-TAR is a reliable and effective method for complex ventral hernias, offering low recurrence and complication rates.
  • Factors like smoking, obesity, and comorbidities are not absolute contraindications.
  • Perioperative management significantly impacts short-term outcomes, supporting PCS-TAR as a preferred method in selected patients.