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Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...

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Related Experiment Video

Updated: Aug 22, 2025

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

Published on: December 28, 2013

A detector block-pairwise dead time correction method for improved quantitation with a dedicated BrainPET scanner.

Ahlam Said Mohamad Issa^1,2,3, Jürgen Scheins¹, Lutz Tellmann¹

¹Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.

Physics in Medicine and Biology

|November 10, 2022

Summary

This summary is machine-generated.

A new block-pairwise dead time correction (DTC) method significantly reduces quantification bias in positron emission tomography (PET) imaging compared to global DTC. This advanced method improves accuracy, especially for brain PET scans.

Failed At:

2026-06-19T13:33:49.221928+00:00

Keywords:

MR/PET systems PET block-pairwise dead time delayed random coincidence time-activity curves

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