Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Anion Transport and Selectivity in Ordered Nanoporous Polymers with 1 nm Scale Charged Pores.

ACS nano·2026

Same author

Targeting mitochondrial-ER homeostasis via autophagy inhibition with celastrol-based nanotherapy for triple-negative breast cancer.

Journal of nanobiotechnology·2026

Same author

From Cation Solvation to Anion Coordination: Lewis-Acidic Boranes Enable Halide Salt Electrolytes.

The journal of physical chemistry. B·2026

Same author

HDAC inhibition sensitizes pancreatic tumors to DNA damage by global redistribution of the transcriptional machinery.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Revealing the Topological Analogy between End-Linked and Pendant Cross-Linked Polymer Networks for Mechanophore-Enabled Toughening.

Journal of the American Chemical Society·2026

Same author

Degradable Vinyl-Based Polymers by Radical Ring-Opening Polymerization: A User Guide.

ACS polymers Au·2026

Search research articles

Related Experiment Video

Updated: Aug 22, 2025

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Published on: June 1, 2016

Hierarchically engineered nanostructures from compositionally anisotropic molecular building blocks.

Ruiqi Liang¹, Yazhen Xue¹, Xiaowei Fu^1,2

¹Department of Chemical and Environmental Engineering, Yale University, New Haven, CT, USA.

Nature Materials

|November 10, 2022

Summary

Researchers developed a molecular self-assembly strategy for creating advanced nanostructured materials. This method allows precise control over nanoscale and mesoscale features for multifunctional materials discovery.

More Related Videos

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Published on: April 1, 2018

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

Related Experiment Videos

Last Updated: Aug 22, 2025

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Published on: June 1, 2016

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Published on: April 1, 2018

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

Area of Science:

Materials Science
Polymer Chemistry
Nanotechnology

Background:

Current limitations in synthesizing hierarchical materials hinder the development of next-generation multifunctional materials.
Independently tailoring nanoscale and mesoscale features remains a significant challenge in materials design.

Purpose of the Study:

To present a predictable molecular self-assembly strategy for crafting nanostructured materials.
To enable the creation of materials with tunable hierarchical morphologies and integrated functionalities.

Main Methods:

Utilizing multicomponent graft block copolymers with sequence-defined side chains as building blocks.
Employing molecular self-assembly to form phase-in-phase hierarchical structures.
Designing graft block copolymer structural parameters to control composition, morphology, and lattice parameters.

Main Results:

Successfully crafted nanostructured materials with diverse phase-in-phase hierarchical morphologies.
Demonstrated broadly tunable nanoscale and mesoscale properties through copolymer design.
Achieved precise integration of multiple functionalities within the assembled nanomaterials.

Conclusions:

The presented strategy offers advanced design principles for efficient hierarchical structure creation.
This facile synthetic platform enables access to complex nanomaterials with precisely integrated functionalities.
Overcomes limitations in synthesizing hierarchical structures for advanced material discovery.