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Published on: December 19, 2020
Radiographic Features of COVID-19 in Children-A Systematic Review.
Niamh Bergin1, Niamh Moore1, Shauna Doyle1
1Discipline of Medical Imaging & Radiation Therapy, University College Cork, T12 AK54 Cork, Ireland.
Chest X-rays (CXRs) in children with COVID-19 frequently show abnormalities, primarily opacification. This review summarizes common radiographic findings in pediatric COVID-19 cases.
Area of Science:
- Radiology
- Pediatric Medicine
- Infectious Diseases
Background:
- The COVID-19 pandemic significantly impacted global health, with varying effects on pediatric populations.
- While less severe than in adults, pediatric COVID-19 cases present distinct clinical and imaging features.
- Frequent imaging, including chest radiography, has been employed in both adult and pediatric patients.
Purpose of the Study:
- To systematically review and summarize the chest radiograph (CXR) findings in pediatric patients diagnosed with COVID-19.
- To provide clinicians and researchers with a comprehensive overview of radiographic features in children with SARS-CoV-19.
- To contribute to understanding the pathophysiology and optimal management of pediatric COVID-19 through imaging analysis.
Main Methods:
- Systematic literature search of four databases (PubMed, Medline, CINAHL, ScienceDirect) from November 2020 to March 2021.
- Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines.
- Inclusion criteria: full-text English articles, confirmed COVID-19, reported CXR findings, pediatric patients (0-18 years), human subjects. Quality assessment using NIH tools.
Main Results:
- Eight studies met the inclusion criteria.
- Over 50% of CXRs in pediatric COVID-19 patients were abnormal in seven of the eight studies.
- Opacification was the most frequent finding (all eight studies), followed by pleural effusion (six studies).
- Consolidation and peri-bronchial thickening were noted in four studies. Common opacifications included consolidation, ground glass, and interstitial patterns.
Conclusions:
- Opacification, particularly consolidation, ground glass, and interstitial opacities, represents the most common CXR finding in pediatric COVID-19.
- Peri-bronchial thickening was observed in pediatric cases, distinguishing it from common adult findings.
- This review offers critical insights into pediatric COVID-19 radiographic appearances, aiding clinical diagnosis and management.
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