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Fighting Cancer around the World: A Framework for Action.

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Cancer care presents global challenges, with disparities in advanced diagnostics like next-generation sequencing (NGS) and real-world evidence (RWE) impacting patient access and outcomes worldwide.

Keywords:
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Area of Science:

  • Oncology
  • Global Health
  • Personalized Medicine

Background:

  • Cancer represents a significant global health challenge, extending beyond Europe to affect regions with fewer resources.
  • Developed nations share common obstacles in cancer care, while less resourced areas face escalating disease burdens.
  • The European Alliance for Personalised Medicine (EAPM) has convened panels to explore diverse aspects of worldwide cancer management.

Purpose of the Study:

  • To examine the broader, yet similar, challenges in global cancer care.
  • To identify prospects and barriers to improving cancer treatment outcomes internationally.
  • To highlight regional variations in key cancer care elements.

Main Methods:

  • Analysis of discussions and findings from European Alliance for Personalised Medicine (EAPM) panels.
  • Comparative review of cancer care practices across different global regions.
  • Identification of key issues including next-generation sequencing (NGS), real-world evidence (RWE), molecular diagnostics, and reimbursement.

Main Results:

  • Significant regional diversity exists in crucial areas such as NGS, RWE, molecular diagnostics, and reimbursement.
  • These variations contribute to disparities in patient access to diagnostics and treatment.
  • Differences in patient engagement and understanding of cancer are also evident globally.

Conclusions:

  • Addressing global cancer requires understanding and mitigating regional disparities in care.
  • Personalized medicine approaches must be adapted to diverse resource settings.
  • Improving global cancer outcomes necessitates collaborative efforts to overcome access and diagnostic barriers.